Mmmmmmm well the majority of the cast grew up in California, so it ranges within that state. Carolina and Jackson are from Jackson County, Texas so they both have that dry Texan country twang. Bongo and Melissa are ambiguously from within 40 miles of New York and that would show if you could hear them.

Then there’s a character named George who after talking a lot with a friend, MC Griffin, it’s been decided he sounds just like Ralph Bakshi… though I don’t think that counts as regional instead of just sounding like Bakshi…